A novel method for the management of patients with heparin-induced thrombocytopaenia during cardiac surgery.

نویسندگان

  • Pankaj Kumar Mishra
  • Asterinos Chnaris
  • Fayaz Mohammed
  • Heyman Luckraz
چکیده

A 63-year old, male patient presented with prosthetic valve endocarditis and developed heparin-induced thrombocytopaenia (HIT) following heparin administration for continuous veno-venous haemofiltration. Use of cardiopulmonary bypass in patients suffering from heparin-induced thrombocytopaenia is difficult and challenging. We report a novel method that allows heparin use in patients diagnosed with HIT using Multiplate platelet analyser and iloprost. Platelet function analysis is complex, poorly standardized and time consuming. Multiplate platelet analyser represents a convenient, safe, reliable and rapid system that allows the assessment of platelet dysfunction. It allows objective demonstration of platelet inhibition before administration of heparin, allowing safe establishment of cardiopulmonary bypass in patients suffering from HIT.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Heparin-induced thrombocytopaenia (HIT)—an overview: what does the nephrologist need to know and do?

In an era where medical and critical care patients are more commonly subject to thromboprophylaxis, prompt recognition and appropriate treatment of Heparin-induced thrombocytopaenia (HIT) is required to reduce the risk of serious thrombotic events. In this issue of the Clinical Kidney Journal, Thong et al. present two cases of HIT after initiation of dialysis therapy with heparin as anticoagula...

متن کامل

The Efficacy of Therapeutic Angiogenesis Using basic Fibroblast Growth Factor in Patients with Coronary Artery Disease: A Double-Blind, Placebo-Controlled Study

Background and Objectives: Complete revascularization is not possible in up to 37% of patients with coronary artery disease (CAD). Therapeutic angiogenesis may be considered as an option in the management of these patients. The aim of the present study was to evaluate the effectiveness and safety of therapeutic angiogenesis using basic fibroblast growth factor in patients with ...

متن کامل

Perioperative changes in platelet count and function in patients undergoing cardiac surgery

Background: Patients undergoing cardiac surgery are at increased risk of bleeding due to multifactorial coagulopathies. In the present study, we aimed at investigating the changes in platelet count and function during and after surgery as well as determining the association of the platelet dysfunction with bleeding and transfusion requirements in these patients.    Methods: A total o...

متن کامل

Surgical management of cardiac tamponade: Is left anterior minithoracotomy really safe and effective?

Objective: Cardiac tamponade is a life-threatening clinical entity that requires an emergency treatment. Cardiac tamponade can be caused both by benign and malignant diseases. A variety of methods have been described for the treatment of these cases from needle-guided pericardiocentesis, balloon-based techniques to surgical pericardiotomy. The Authors report their experience in...

متن کامل

Srčna Operacija Pri Bolniku S Heparinom Povzročeno Trombocitopenijo Heparin Induced Thrombocytopenia and Cardiac Surgery

Background Heparin induced thrombocytopenia (HIT) is a serious complication related to the heparin treatment and might lead to the life-threatening consequences such as arterial and venous thrombosis. The patient with HIT scheduled for cardiac surgery represents serious problem because heparin, most common used anticoagulation drug during cardiac surgery, must be avoided. Conclusions From the r...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Interactive cardiovascular and thoracic surgery

دوره 18 6  شماره 

صفحات  -

تاریخ انتشار 2014